Which thalassemia is worse?
Last Update: May 30, 2022
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Asked by: Larue Stark
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What is the most severe thalassemia?
In alpha-thalassemia, the severity of thalassemia you have depends on the number of gene mutations you inherit from your parents. The more mutated genes, the more severe your thalassemia. In beta-thalassemia, the severity of thalassemia you have depends on which part of the hemoglobin molecule is affected.
Can alpha thalassemia get worse?
Symptoms can worsen with fever. They can also get worse if you are exposed to certain medicines, chemicals, or infectious agents. Blood transfusions are often needed. You have a greater risk of having a child with alpha thalassemia major.
Which thalassemia is most common?
Beta thalassemia is a fairly common blood disorder worldwide. Thousands of infants with beta thalassemia are born each year. Beta thalassemia occurs most frequently in people from Mediterranean countries, North Africa, the Middle East, India, Central Asia, and Southeast Asia.
Which thalassemia is dangerous?
Beta thalassemia major (also called Cooley's anemia). People with beta thalassemia major have severe symptoms and life-threatening anemia. They need regular blood transfusions and other medical treatment.
Beta Thalassemia - causes, symptoms, diagnosis, treatment, pathology
How long do thalassemia patients live?
“Most thalassaemia patients would live up to the age of 25 to 30 years. Improved facilities will help them live up to the age of 60,” said Dr Mamata Manglani, head of pediatrics, Sion hospital.
Can thalassemia be cured?
Bone marrow and stem cell transplant from a compatible related donor is the only treatment that can cure thalassemia. It is the most effective treatment.
Does thalassemia weaken immune system?
Because it is working so hard on this job, it can't work as hard to filter blood or monitor for and fight infections. Because of this, people with thalassemia are said to be “immunocompromised,” which means that some of the body's defenses against infection aren't working.
Can you donate blood if you have thalassemia?
If you have G6PD (Glucose-6-Phosphate Dehydrogenase Deficiency) or Thalassemia (minor), you can donate blood if you meet the haemoglobin requirement.
Can thalassemia minor get married?
People suffering with Thalassemia can marry any other person of their choice and live a normal family life and yes, even have babies! A Thalassemia patient may have a good reproductive health if proper care is taken from the very beginning of the patient's life.
What should I eat if I have alpha thalassemia?
Nutrition & Thalassemia
It is recommended that patients going through blood transfusion should opt for a low iron diet. Avoiding iron-fortified foods like cereal, red meat, green leafy vegetables & Vitamin C-rich foods is the best option for thalassemic patients.
Is alpha thalassemia a disability?
Alpha thalassemia/intellectual disability chromosome 16 (ATR-16) syndrome is an extremely rare disorder characterized by intellectual disability, which is milder than in ATR-X syndrome, and alpha thalassemia, which is more severe than in ATR-X syndrome.
Is milk good for thalassemia?
Calcium. Many factors in thalassaemia promote calcium depletion. A diet containing adequate calcium (e.g. milk, cheese, dairy products and kale) is always recommended.
What part of the body does thalassemia affect?
Thalassemia can cause bone deformities in the face and skull. People who have thalassemia may also have severe osteoporosis (brittle bones). Too much iron in your blood. This can cause damage to the heart, liver, or endocrine system (glands in the body that make hormones, like the thyroid gland and adrenal glands).
What is the best treatment for thalassemia?
- Frequent blood transfusions. More severe forms of thalassemia often require frequent blood transfusions, possibly every few weeks. ...
- Chelation therapy. This is treatment to remove excess iron from your blood. ...
- Stem cell transplant.
Is thalassemia linked to leukemia?
The occurrence of thalassemia with leukemia is a rare event. Voskaridou et al. report a 32 years old man with thalassemia major whose leukocytosis and thrombocytosis were gradually increased and leading to a diagnosis of chronic myelogenous leukemia .
Can people with thalassemia minor donate?
Usually, individuals with hemoglobin levels that are too low are temporarily not permitted to donate blood. A low hematocrit level is one of the most common reason people are temporarily disqualified or “deferred” from donating blood, but some donors can actually have anemia and still be eligible to donate.
Can thalassemia patients get pregnant?
Can You Get Pregnant With Beta Thalassemia? Yes, but you may need help getting pregnant. Often, women with beta thalassemia will need to use medications to help them ovulate in order to become pregnant. Many health problems caused by beta thalassemia have to do with too much iron in your body.
Where does alpha thalassemia come from?
Alpha thalassemia typically results from deletions involving the HBA1 and HBA2 genes. Both of these genes provide instructions for making a protein called alpha-globin, which is a component (subunit) of hemoglobin . People have two copies of the HBA1 gene and two copies of the HBA2 gene in each cell.
At what age is thalassemia detected?
Share on Pinterest Thalassemia is an inherited blood disorder. Most children with moderate to severe thalassemia receive a diagnosis by the time they are 2 years old. People with no symptoms may not realize that they are carriers until they have a child with thalassemia.
Is vitamin C bad for thalassemia?
If you have repeated blood transfusions, it's possible for your body to get too much iron. This can damage your heart and other organs. Make sure to avoid vitamins that contain iron, and don't take extra vitamin C, which can increase how much iron you absorb from food.
Does thalassemia affect blood pressure?
Pulmonary hypertension in β-thalassemia major correlates with the severity of hemolysis, yet in patients whose disease is well treated with chronic transfusion therapy, the development of pulmonary hypertension can be related to cardiac dysfunction and the subsequent toxic effects of iron overload rather than hemolysis ...
How do I know if I have thalassemia carrier?
You can find out if you're a carrier of thalassaemia by having a simple blood test. The NHS Sickle Cell and Thalassaemia Screening Programme also has detailed leaflets about being a beta thalassaemia carrier or a delta beta thalassaemia carrier.
How do you get thalassemia?
Thalassemia is an inherited (i.e., passed from parents to children through genes) blood disorder caused when the body doesn't make enough of a protein called hemoglobin, an important part of red blood cells.
Does thalassemia shorten life expectancy?
In the mild form of the disease, thalassemia minor (heterozygous β-thalassemia), there is usually only slight or no anemia, and life expectancy is normal. Occasionally, complications occur involving slight enlargement of the spleen.