Could thalassemia have been prevented?

Last Update: May 30, 2022

This is a question our experts keep getting from time to time. Now, we have got the complete detailed explanation and answer for everyone, who is interested!

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Can thalassemia be prevented? Currently, thalassemia cannot be prevented because it is an inherited (passed down from parents to the child) blood disorder. It is possible to identify carriers of this disorder with genetic testing.

Can alpha thalassemia be prevented?

Key points about alpha thalassemia

This condition causes mild to severe anemia, based on the type of alpha thalassemia that is inherited. People who have this condition can pass the disease on to their children. There is no cure.

Is thalassemia always genetic?

In general, thalassemia is inherited in an autosomal recessive manner; however, the inheritance can be quite complex as multiple genes can influence the production of hemoglobin. Most people affected by beta thalassemia have mutations in both copies of the HBB gene in each cell .

Can you survive thalassemia?

Survival of thalassemia patients

The cumulative survival rate from birth until 10 years old was 99%. After reaching the age of 20 years, 88% of the patients survived until 30 years, 74% survived until 45, 68% survived until 50, and 51% survived until 55 years old.

What race is thalassemia most common in?

Thalassemia is passed from parents to children through mutated hemoglobin genes. Certain ancestry. Thalassemia occurs most often in African Americans and in people of Mediterranean and Southeast Asian descent.

What is Thalassemia and How can it be prevented? - Dr. Satish Kumar

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Does thalassemia weaken immune system?

Because it is working so hard on this job, it can't work as hard to filter blood or monitor for and fight infections. Because of this, people with thalassemia are said to be “immunocompromised,” which means that some of the body's defenses against infection aren't working.

Is thalassemia a serious disease?

A person with thalassemia will have too few red blood cells and too little hemoglobin, and the red blood cells may be too small. The impact can range from mild to severe and life-threatening. Around 100,000 newborns are delivered each year with severe forms of thalassemia.

Can thalassemia major Be Cured?

A stem cell transplant is the only treatment that can cure thalassemia. But only a small number of people who have severe thalassemias are able to find a good donor match and have the risky procedure. For more information, go to the Health Topics Blood and Marrow Stem Cell Transplant article.

How many years do thalassemia patients live?

“Most thalassaemia patients would live up to the age of 25 to 30 years. Improved facilities will help them live up to the age of 60,” said Dr Mamata Manglani, head of pediatrics, Sion hospital.

Can thalassemia cause weight gain?

They do not gain weight and grow at the expected rate (failure to thrive) and may develop yellowing of the skin and whites of the eyes (jaundice). Affected individuals may have an enlarged spleen, liver, and heart, and their bones may be misshapen. Some adolescents with thalassemia major experience delayed puberty.

Can you have a baby if you have thalassemia?

Can You Get Pregnant With Beta Thalassemia? Yes, but you may need help getting pregnant. Often, women with beta thalassemia will need to use medications to help them ovulate in order to become pregnant. Many health problems caused by beta thalassemia have to do with too much iron in your body.

Can thalassemia minor get married?

People suffering with Thalassemia can marry any other person of their choice and live a normal family life and yes, even have babies! A Thalassemia patient may have a good reproductive health if proper care is taken from the very beginning of the patient's life.

Is thalassemia linked to leukemia?

The occurrence of thalassemia with leukemia is a rare event. Voskaridou et al. report a 32 years old man with thalassemia major whose leukocytosis and thrombocytosis were gradually increased and leading to a diagnosis of chronic myelogenous leukemia [4].

What should I eat if I have alpha thalassemia?

Nutrition & Thalassemia

It is recommended that patients going through blood transfusion should opt for a low iron diet. Avoiding iron-fortified foods like cereal, red meat, green leafy vegetables & Vitamin C-rich foods is the best option for thalassemic patients.

Is milk good for thalassemia?

Calcium. Many factors in thalassaemia promote calcium depletion. A diet containing adequate calcium (e.g. milk, cheese, dairy products and kale) is always recommended.

Is thalassemia an autoimmune disease?

Autoimmune diseases do occur in thalassemia patients, but a causal relationship between a thalassemia diagnosis and the incidence and severity of autoimmune diseases cannot yet be fully established with the available evidence.

Does thalassemia shorten life expectancy?

In the mild form of the disease, thalassemia minor (heterozygous β-thalassemia), there is usually only slight or no anemia, and life expectancy is normal. Occasionally, complications occur involving slight enlargement of the spleen.

How does thalassemia affect everyday life?

People who have mild or minor forms of thalassemia can typically lead normal lives. In severe cases, heart failure is a possibility. Other complications include liver disease, abnormal skeletal growth, and endocrine issues.

Is thalassemia more common in males or females?

Thalassemia can affect both men and women. Certain ethnic groups are at greater risk: Alpha thalassemia most often affects people who are of Southeast Asian, Indian, Chinese, or Filipino descent.

What is the best treatment for thalassemia?

For moderate to severe thalassemia, treatments might include:
  • Frequent blood transfusions. More severe forms of thalassemia often require frequent blood transfusions, possibly every few weeks. ...
  • Chelation therapy. This is treatment to remove excess iron from your blood. ...
  • Stem cell transplant.

What's the best treatment for thalassemia?

Nutritional supplements, in the form of folic acid supplements, and monitoring of B12 levels are important, as these nutrients are key components to making healthy blood cells. Bone marrow and stem cell transplant from a compatible related donor is the only treatment that can cure thalassemia.

What is the theme of World thalassemia Day 2020?

The theme for the International Thalassaemia Day 2020 is - 'The dawning of a new era for thalassaemia' which states that it is time for a global effort to make novel therapies accessible and affordable to patients.

How does a person get thalassemia?

Thalassemia is an inherited (i.e., passed from parents to children through genes) blood disorder caused when the body doesn't make enough of a protein called hemoglobin, an important part of red blood cells.

Can you donate blood if you have thalassemia?

If you have G6PD (Glucose-6-Phosphate Dehydrogenase Deficiency) or Thalassemia (minor), you can donate blood if you meet the haemoglobin requirement.

How do you know if you have thalassemia?

Diagnosis. Doctors diagnose thalassemias using blood tests, including a complete blood count (CBC) and special hemoglobin tests. A CBC measures the amount of hemoglobin and the different kinds of blood cells, such as red blood cells, in a sample of blood.