Are thalassemia and sickle cell the same?

Last Update: May 30, 2022

This is a question our experts keep getting from time to time. Now, we have got the complete detailed explanation and answer for everyone, who is interested!

Asked by: Prof. Consuelo Waelchi II
Score: 4.7/5 (37 votes)

Beta thalassemia disease is not a form of sickle cell disease, but it is a serious lifelong illness. People who have beta thalassemia disease do not make enough hemoglobin. The amount of hemoglobin a child can produce, determines whether a child has: Beta Thalassemia Intermedia.

Can you have sickle cell and thalassemia?

People affected by sickle beta thalassemia inherit a different mutation in the HBB gene from each parent: one that produces sickle hemoglobin (called sickle trait ) and a second that results in reduced levels of functional hemoglobin (called beta thalassemia).

Are you a sickle cell or thalassemia carrier?

People only have sickle cell disease or thalassaemia if they inherit 2 unusual haemoglobin genes: 1 from their mother and 1 from their father. People who inherit just 1 unusual gene are known as carriers or as having a trait. Carriers are healthy and do not have the disease.

What is thalassemia and sickle cell?

Sickle cell disease and thalassemia are genetic disorders caused by errors in the genes for hemoglobin, a substance composed of a protein ("globin") plus an iron molecule ("heme") that is responsible for carrying oxygen within the red blood cell.

Is sickle cell curable?

Stem cell or bone marrow transplants are the only cure for sickle cell disease, but they're not done very often because of the significant risks involved. Stem cells are special cells produced by bone marrow, a spongy tissue found in the centre of some bones. They can turn into different types of blood cells.

Sickle cell anemia - causes, symptoms, diagnosis, treatment & pathology

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How long can a person live with sickle cell disease?

With a national median life expectancy of 42–47 years, people with sickle cell disease (SCD) face many challenges, including severe pain episodes, stroke, and organ damage.

Can you have a baby if you have thalassemia?

Can You Get Pregnant With Beta Thalassemia? Yes, but you may need help getting pregnant. Often, women with beta thalassemia will need to use medications to help them ovulate in order to become pregnant. Many health problems caused by beta thalassemia have to do with too much iron in your body.

How do I know if I am a thalassemia carrier?

You can find out if you're a carrier of thalassaemia by having a simple blood test. The NHS Sickle Cell and Thalassaemia Screening Programme also has detailed leaflets about being a beta thalassaemia carrier or a delta beta thalassaemia carrier.

Can thalassemia minor get married?

People suffering with Thalassemia can marry any other person of their choice and live a normal family life and yes, even have babies! A Thalassemia patient may have a good reproductive health if proper care is taken from the very beginning of the patient's life.

Can thalassemia turn into leukemia?

Occurrence of leukemia in thalassemia major is a rare presentation. Here we report two cases of thalassemic patients, developing acute lymphoblastic leukemia. The genetic analysis revealed that, female and male patients were homozygous for IVSI-6 and IVSI-5, respectively.

What blood type is sickle cell trait?

It is an inherited condition in which both hemoglobin A and S are produced in the red blood cells, always more A than S. Individuals with sickle cell trait are generally healthy.

Can 2 sickle cell carriers get married?

When both individuals are sickle cell carriers, the church discourages them from marrying. Some church denominations, especially in Enugu state, go further and refuse to wed couples when both individuals are sickle cell carriers.

Does thalassemia minor affect fertility?

Although spontaneous fertility can occur in well-transfused and well-chelated patients with thalassemia, infertility mainly due to HH still remains one of the most common morbidities and obstacles for having children [9,10,11,12,13,14,15]. In our cohort, male and female fertility rates were 50%.

Can thalassemia patients get married?

Aim: With good care, patients with transfusion-dependent thalassemia major (TDTM) can reach older ages, marry and reproduce.

What should we eat in thalassemia minor?

Nutrition & Thalassemia

It is recommended that patients going through blood transfusion should opt for a low iron diet. Avoiding iron-fortified foods like cereal, red meat, green leafy vegetables & Vitamin C-rich foods is the best option for thalassemic patients.

How long do thalassemia patients live?

“Most thalassaemia patients would live up to the age of 25 to 30 years. Improved facilities will help them live up to the age of 60,” said Dr Mamata Manglani, head of pediatrics, Sion hospital.

At what age is thalassemia detected?

Share on Pinterest Thalassemia is an inherited blood disorder. Most children with moderate to severe thalassemia receive a diagnosis by the time they are 2 years old. People with no symptoms may not realize that they are carriers until they have a child with thalassemia.

Can thalassemia be cured?

Bone marrow and stem cell transplant from a compatible related donor is the only treatment that can cure thalassemia. It is the most effective treatment.

Can 2 people with thalassemia have a baby?

If two people who are carriers of the same type of thalassaemia have children, their children have a: 25 per cent risk of developing thalassaemia major because they inherited the thalassaemia gene from both parents.

Is milk good for thalassemia?

Calcium. Many factors in thalassaemia promote calcium depletion. A diet containing adequate calcium (e.g. milk, cheese, dairy products and kale) is always recommended.

Does thalassemia cause miscarriage?

Miscarriage occurs mostly in cases of thalassemia homozygous fetuses or those with severe IUGR.

How old is the oldest living person with sickle cell?

The oldest person currently living with sickle cell, Asiata Onikoyi-Laguda, is 94.

Does sickle cell get worse with age?

SCD is a disease that worsens over time. Treatments are available that can prevent complications and lengthen the lives of those who have this condition.

Can a white person have sickle cell?

Answer. Yes, they can. Sickle cell disease can affect people of ANY race or ethnicity. Sickle cell disease, an inherited disorder of the red blood cells, is more common in African Americans in the U.S. compared to other ethnicities—occurring in approximately 1 in 365 African Americans.

Can thalassemia minor affect your period?

Puberty may be delayed or progress abnormally in teenagers with thalassemia, due to iron build up impairing the function of the pituitary gland. This may lead to complications such as: Absence of menstruation, known as amenorrhea.